Open - Ph.D. Student Position
Institute for Basic Science at the KAIST Campus
Our vision is to make groundbreaking discoveries, conceptual advances and paradigm shifts in understanding the central nervous system (CNS) and brain vascularture through basic and fundamental research
Identifying organ-specific vascular heterogeneity and remodeling processes
Elucidating the structure, regulatory mechanisms, and roles of lymphatic vessels as cerebrospinal fluid (CSF) drainage pathways in brain diseases and aging
Investigating the principles of brain homeostasis regulated by neuroimmune interactions
Investigating the mechanisms of CNS antigen clearance and regulation via the brain’s blood vessels and lymphatic system
Understanding neurovascular-immune interactions in Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and glioblastoma
Director Gou Young Koh won the ‘LE&RN-GRC Lifetime Achievement Award' at the Gordon Research Conference, Lymphatics
Director Gou Young Koh won the ‘LE&RN-GRC Lifetime Achievement Award' at the 2026 Gordon Research Conference on Lymphatics.
The LE&RN-GRC Lifetime and Career Achievement Awards in Lymphatic Research are intended to recognize those individuals who have made a significant contribution to the promotion and support of lymphatic research, to advancing lymphatic research and/or finding improved treatments and cures for lymphatic diseases (LD), lymphedema (LE), lipedema (LI), and related diseases.
The Lifetime Achievement Award is presented to an individual who has had a lifetime of outstanding achievements in the field of lymphatics and who must have a career spanning over 20 years.
March 05, 2026Prof. Won-Suk Chung of IBS Center for Vascular Research Receives Grand Prize at 20th Life's Mystery Award
Established in 2006 by the Bioethics Committee of the Catholic Archdiocese of Seoul, the award honors individuals and organizations that uphold the dignity of human life. Prof. Chung was recognized for his pioneering contributions at the intersection of neuroimmunology and neuroscience.
His research has demonstrated that astrocytes and microglia play key roles in remodeling neural circuits and maintaining brain homeostasis, and that glial dysfunction is linked to conditions such as epilepsy, stroke, depression, and Alzheimer's disease — pointing toward new therapeutic possibilities.
The award ceremony will be held on June 9 at the Seoul St. Mary's Hospital Campus of The Catholic University of Korea.
May 11, 2026An article titled “Cooperative ETS transcription factors are required for lymphatic endothelial cell integrity and resilience” has recently been published in Journal of Clinical Investigation
An article titled "Cooperative ETS transcription factors are required for lymphatic endothelial cell integrity and resilience" is published in Journal of Clinical Investigation.
Co-first authors Myung Jin Yang and Seok Kang, along with their research team at the IBS Center for Vascular Research, have identified the transcription factors Erg and Fli1 as essential cooperative regulators of the lymphatic system.
Their study demonstrates that the combined loss of these factors in adult mice leads to fatal lymphatic failure, impaired immune cell trafficking, and chronic inflammation. By linking these genetic mechanisms to human conditions like lymphedema, the authors establish Erg and Fli1 as the core "switches" required for lymphatic identity, functional resilience, and injury repair.
March 02, 2026Newly published in Nature Communications: “Motor learning and dopamine-dependent striatal synaptic plasticity are controlled by astrocytic MEGF10”
A study recently published in Nature Communications by a research team led by Won-Suk Chung (IBS) and Jae-Ick Kim (UNIST) reveals that astrocytes are key players in motor skill acquisition. The research, titled “Motor learning and dopamine-dependent striatal synaptic plasticity are controlled by astrocytic MEGF10,” identifies a new cellular mechanism for brain plasticity.
The team, including first author Young-Jin Choi, discovered that a specific receptor on astrocytes called MEGF10 is responsible for "pruning" or removing unnecessary synapses in the striatum during learning. While dopamine signals which connections to strengthen, astrocytes ensure efficiency by clearing away unnecessary synaptic "noise" via MEGF10. When this receptor was removed in animal models, the ability to learn new physical tasks and the brain's synaptic plasticity were significantly impaired.
These findings suggest that successful learning requires not only the strengthening of neural signals by dopamine but also the active structural refinement by astrocytes, offering new insights for treating motor-related neurological disorders.
February 23, 2026Nasal ciliated cells are primary targets for SARS-CoV-2 replication in early stage of COVID 19
Lymphatic vessel in lacteal