"Increased CSF drainage by non-invasive manipulation of cervical lymphatics" is published in Nature.  

The Nature article titled "Increased CSF drainage by non-invasive manipulation of cervical lymphatics" explores a novel method to enhance cerebrospinal fluid (CSF) drainage using non-invasive mechanical stimulation. Researchers discovered that applying controlled mechanical pressure to the neck area of aged mice significantly improved CSF outflow through superficial cervical lymphatics, effectively restoring impaired drainage associated with aging. This technique holds promise for developing therapeutic strategies aimed at treating neurodegenerative conditions linked to reduced CSF clearance, such as Alzheimer's disease.

The research was conducted by a team from the Institute for Basic Science (IBS) in Korea, led by Dr. Gou Young Koh, Director of the IBS Center for Vascular Research. The first authors are Dr. Hokyung Jin, Dr. Jin-Hui Yoon, and Dr. Seon Pyo Hong. Their work highlights the potential of non-invasive mechanical stimulation as a therapeutic approach for enhancing brain waste clearance.

For more detailed information, you can access the full article here: Nature Article. 

New review article titled "Advances and controversies in meningeal biology" is published in Nature Neuroscience

An article "Advances and controversies in meningeal biology" by Christer Betsholtz, Britta Engelhardt, Gou Young Koh, Donald M. McDonald, Steven T. Proulx and Julie Siegenthaler, all authors equally contributed, has been published in Nature Neuroscience, exploring the latest developments and debates in meningeal research. 

This review examines the dura, arachnoid, and pia mater as the key layers of the meninges that protect the brain and spinal cord. It highlights the recent discovery of molecularly distinct fibroblast types in each meningeal layer, and discusses the ongoing debates about the routes and flow dynamics of cerebrospinal fluid clearance through peripheral lymphatics and lymph nodes. The review also considers the advances and controversies in meningeal immune functions, aiming to identify the hallmarks of meningeal pathophysiology to develop a more complete understanding of the meninges in both health and disease.

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Lymphatic vessel in lacteal