A new review article, "Cerebrospinal fluid draining lymphatics in health and disease: advances and controversies", has been published in Nature Cardiovascular Research.  

Our research center has published a review in Nature Cardiovascular Research entitled “Cerebrospinal fluid draining lymphatics in health and disease: advances and controversies.” The article highlights the emerging recognition of meningeal lymphatic vessels as a major outflow route for cerebrospinal fluid (CSF) clearance, outlining their structural and functional diversity, regulatory mechanisms, and connections with intracranial and extracranial compartments. It further discusses how impaired CSF drainage contributes to the aging brain, neurodegenerative and immune disorders, traumatic brain injury, and stroke, while emphasizing therapeutic opportunities and unresolved controversies in the field.

For more detailed information, you can access the full article here: Nature Cardiovascular Research.   

"Increased CSF drainage by non-invasive manipulation of cervical lymphatics" is published in Nature.  

The Nature article titled "Increased CSF drainage by non-invasive manipulation of cervical lymphatics" explores a novel method to enhance cerebrospinal fluid (CSF) drainage using non-invasive mechanical stimulation. Researchers discovered that applying controlled mechanical pressure to the neck area of aged mice significantly improved CSF outflow through superficial cervical lymphatics, effectively restoring impaired drainage associated with aging. This technique holds promise for developing therapeutic strategies aimed at treating neurodegenerative conditions linked to reduced CSF clearance, such as Alzheimer's disease.

The research was conducted by a team from the Institute for Basic Science (IBS) in Korea, led by Dr. Gou Young Koh, Director of the IBS Center for Vascular Research. The first authors are Dr. Hokyung Jin, Dr. Jin-Hui Yoon, and Dr. Seon Pyo Hong. Their work highlights the potential of non-invasive mechanical stimulation as a therapeutic approach for enhancing brain waste clearance.

For more detailed information, you can access the full article here: Nature Article. 

Nasal ciliated cells are primary targets for SARS-CoV-2 replication in early stage of COVID 19

Lymphatic vessel in lacteal